Advanced Skin Technology is excited to announce the release of BIOJUVE™, a skin biome brand that uses Xycrobe™ technology, a clinically-proven living microbe technology for healthier, younger-looking skin.

BIOJUVE™ is skin science like never experienced before. Created by Crown Laboratories, Inc. – the founders of SkinPen® – and pioneered by skin scientists, BIOJUVE™ is endorsed by internationally recognised board-certified dermatologists and is the leading edge of natural, biological innovation.

Formulated specifically to address the skin biome, BIOJUVE™ uses a microbial patented technology Xycrobe™ to naturally produce and deliver Bioessentials™ such as proteins, polypeptides, and antioxidants to optimise skin health and vitality. The Xycrobe™ technology used in BIOJUVE™ targets certain skin conditions and cosmetic treatments using an isolated, living strain of skin-relevant bacteria.

About Xycrobe™ technology

‘Xycrobe is a patented technology that harnesses living microbes developed to enhance the skin’s microbiome for optimised skin health. Xycrobe™ Technology lives and thrives both on the skin’s surface and deep within the hair follicles.

“Crown’s significant investment in skin biome research proves our deep commitment to skin science for life,” says Dr. Thomas M. Hitchcock, Chief Science Officer at Crown Laboratories, Inc. “We’ve spent the last decade developing the Xycrobe™ technology and formulating it into the BIOJUVE brand products with the philosophy that human skin is an ecosystem and should be cared for as such. What we have found is that this holistic approach to caring for the skin biome (including the skin, the skin microbiome, and the environment of the skin) goes beyond traditional skincare and can vastly improve the skin biome’s overall health and beauty. This is reflected in our pre-clinical and clinical research which was published in The Journal of Cosmetic Dermatology in November 2022. We are proud to be an innovator in the skin biome-care space and feel that BIOJUVE will be the leading solution on the market for this emerging field.”

“BIOJUVE’s Xycrobe™ technology is a groundbreaking development in skincare and skin health,” says Dr. Doris Day, a board-certified dermatologist in the U.S. “As a dermatologist who has consulted on product development for many brands during my career, I’m very optimistic about the possibilities BIOJUVE offers to better address our patients’ skin conditions. Furthermore, the technology and deep-rooted science harnessed in BIOJUVE brings a new perspective to medical literature, the field of dermatology, and the wider topical skincare category.”

The Biojuve™ Range

BIOJUVE™ is a complete skin biome range consisting of 5 topical products designed to work together to optimize skin health on and below the surface.  BIOJUVE™ is available from September 11 2023 in Australia and New Zealand.

BIOJUVE™ Conditioning Cleanse – This non-foaming conditioning cleanser effectively removes dirt and impurities while also helping to preserve and promote a thriving microbiome for optimal skin health. This innovative cleanser helps to keep skin naturally balanced and well-conditioned while also supporting the living microbe technology found in BIOJUVE Living Biome Essentials Serum. AUD RRP $59.00, 100ml / NZD RRP $69.00, 100ml

BIOJUVE™ Conditioning Cleanse

BIOJUVE™ Biome Support Complex – BIOJUVE Support Complex is a supplemental, extracted blend of microbe-derived proteins, polypeptides and antioxidants that helps to support and enhance the living microbe technology found in the Living Biome Essentials Serum. AUD RRP $189.00, 30ml / NZD RRP $209.00, 30ml

BIOJUVE™ Biome Support Complex

BIOJUVE™ Hydrating Barrier Cream: This lightweight, moisturizing Hydrating Barrier Cream comes in two versions, Normal-to-Dry and Normal-to-Oily. Both versions were designed to enhance the performance of BIOJUVE Living Biome Essentials Serum by protecting the living microbe technology from disruption caused by common ingredients found in makeup and sunscreen. AUD RRP $99.00, 50ml / NZD RRP $109.00, 50ml

BIOJUVE™ Hydrating Barrier Cream

BIOJUVE™ Living Biome Essentials Duo:  This duo contains two products, the BIOJUVE Living Biome Essentials Serum and the BIOJUVE Activating Mist.  The BIOJUVE Living Biome Essentials Serum hosts the living microbe technology Xycrobe™ and the Activating Mist acts as an “on” switch to activate the living microbe technology found in the Living Biome Essentials Serum.  This powerhouse duo was designed to enhance the skin’s microbiome, target ageing skin concerns and optimising skin health.  AUD RRP $299.00 / NZD RRP $339.00

BIOJUVE™ Living Biome Essentials Duo

For more information and stockists: Australia –, New Zealand –